原子光谱线变宽的因素分析

分别从经典理论和量子理论的不同角度论述了使原子光谱线变宽的各种主要因素:由于能量的不确定关系导致的自然致宽;多普勒致宽;碰撞致宽;因碰撞过程中原子能级变化而导致的压力致宽、场致宽等.通过分析,阐明了实际光谱线与理想光谱线的不同及其原因.     

Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer

The fraction of pyruvate dehydrogenase complex (PDC) in the active form is reduced by the activities of dedicated PD kinase isozymes (PDK1, PDK2, PDK3 and PDK4). Via binding to the inner lipoyl domain (L2) of the dihydrolipoyl acetyltransferase (E2 60mer), PDK rapidly access their E2-bound PD substrate. The E2-enhanced activity of the widely distributed PDK2 is limited by dissociation of ADP from its C-terminal catalytic domain, and this is further slowed by pyruvate binding to the N-terminal regulatory (R) domain. Via the reverse of the PDC reaction, NADH and acetyl-CoA reductively acetylate lipoyl group of L2, which binds to the R domain and stimulates PDK2 activity by speeding up ADP dissociation. Activation of PDC by synthetic PDK inhibitors binding at the pyruvate or lipoyl binding sites decreased damage during heart ischemia and lowered blood glucose in insulin-resistant animals. PDC activation also triggers apoptosis in cancer cells that selectively convert glucose to lactate. Received 25 August 2006; received after revision 20 November 2006; accepted 20 December 2006     

空调水泵变频调节的变压差控制研究

水泵变频的变压差控制就是使压差随着流量的减少而减小,保持管路特性曲线不变,尽量减少系统的无用能耗。实例计算表明,与定压差控制相比,变压差控制需要增加的成本不多,节省的能耗却多了一倍。     

圆钢管混凝土构件在侧向冲击下的动塑性极限弯矩的研究

利用有限元软件ANSYS/DYNA,模拟了悬臂和简支钢管混凝土构件的侧向冲击数值,计算了动塑性极限弯矩。     

NaH分子基态(X1∑+)的分子结构与势能函数

用量子化学计算方法与基组CCSD(T)/6-311 G(3DF,2PD)、QCISD(T)/6-311 G(3DF,2P)、QCISD(T)/aug-cc-pvtz和CCSD(T)/cc-pvtz,优化计算了NaH分子基态的平衡结构和离解能,得到的平衡核间距与实验值基本吻合。采用Murrell-Sorbie函数的修正式进行非线性最小二乘法拟合,得到了NaH分子势能函数的解析表达式,并进一步计算出NaH分子的力常数及光谱常数;计算结果与实验数据非常吻合。     

在随动曲线坐标系下模拟矩形坯压缩变形的能量法

本文提出一种新的模拟塑性流动的数值法-__在随动曲线坐标系下的能量法.运动学可能速度场、变形总功率泛函以张量形式表达在随动曲线坐标系上,通过优化可变参数使泛函达最小值,以求得变形过程中速度场、位移增量场和最终位移场.根据上述算法和所编制的FORTRAN程序,本文计算了平板间矩形坯压缩变形的位移场.计算结果得到实验验证.     

太阳能制冷降温技术在我区开发利用的前景

指出利用太阳能制冷降温的优越性，介绍各种太阳能制冷方案．分析广西的气候特点．介绍引进ＯＭ太阳房技术，设计符合本地条件的太阳能去湿降温建筑．     

碱土金属化合物晶格能计算的新方法——离子贡献法

本文提出了一种计算碱土金属化合物品格能的新方法——离子贡献法。该方法只需本文提供的离子贡献值即可计算得到晶格能,而不需要任何实验数据。对碱土金属氧化物、卤化物、氢化物、氢氧化物、硫酸盐、碳酸盐、磷酸盐等十九类75种化合物的计算结果表明,计算值与实验值之间的一致性令人满意,计算结果的平均相对误差仅0.79%,小于目前已有的所有方法的计算误差。     

关于固体的焓H和自由能G的讨论

按照弹性理论，将平均压力作为体系的流体静力学压力，进而得出熔Ｈ和自由能Ｇ的新定义。通过对功的计算证明这是合理的．从而扩大了Ｈ和Ｇ的应用范围。     

Family I.3 lipase: bacterial lipases secreted by the type I secretion system

Based on the classification of bacterial lipolytic enzymes, family I.3 lipase is a member of the large group of Gram-negative bacterial true lipases. This lipase family is distinguished from other families not only by the amino acid sequence, but also by the secretion mechanism. Lipases of family I.3 are secreted via the well-known type I secretion system. Like most of proteins secreted via this system, family I.3 lipases are composed of two domains with distinct yet related functions. Recent years have seen an increasing amount of research on this lipase family, in terms of isolation, secretion mechanism, as well as biochemical and biophysical studies. This review describes our current knowledge on the structure-function relationships of family I.3 lipase, with an emphasis on its secretion mechanism. Received 18 April 2006; received after revision 3 July 2006; accepted 24 August 2006